A national, multi-centre study evaluating Thrombotic Thrombocytopenia Syndrome (TTS) associated with ChAdOx1 (AZD1222) and other SARS-CoV-2 vaccines (viral vector and m-RNA)

  • Funded by Medical Research Future Fund (MRFF)
  • Total publications:0 publications

Grant number: unknown

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Key facts

  • Disease

    COVID-19
  • Known Financial Commitments (USD)

    $2,151,643.58
  • Funder

    Medical Research Future Fund (MRFF)
  • Principal Investigator

    Unspecified Unspecified Unspecified
  • Research Location

    Australia
  • Lead Research Institution

    N/A
  • Research Priority Alignment

    N/A
  • Research Category

    Vaccines research, development and implementation

  • Research Subcategory

    Adverse events associated with immunization

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

A condition of a blood clot with low platelets has been described in some patients after receiving COVID-19 vaccines, including the widely available ChAdOx1 vaccine. Known as thrombosis with thrombocytopenia syndrome (TTS), this condition presents with a wide spectrum of severity. Although it has an immunological basis, the underlying mechanisms is unknown and there are no known predictors for increased risk of TTS. Further understanding is needed to ensure safe COVID-19 vaccination.