Estimating a Time-to-Event Distribution from Right-Truncated Data in an Epidemic: a Review of Methods
- Funded by UK Research and Innovation (UKRI)
- Total publications:0 publications
Grant number: C19-IUC-537
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Key facts
Disease
COVID-19Funder
UK Research and Innovation (UKRI)Principal Investigator
Dr. Shaun SeamanResearch Location
United KingdomLead Research Institution
MRC Biostatistics UnitResearch Priority Alignment
N/A
Research Category
Epidemiological studies
Research Subcategory
Disease surveillance & mapping
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
Time-to-event data are right-truncated if only individuals who have experienced the event by a certain time can be included in the sample. For example, we may be interested in estimating the distribution of time from onset of disease symptoms to death and only have data on individuals who have died. This may be the case at the beginning of an epidemic. Right truncation causes the distribution of times to event in the sample to be biased towards shorter times compared to the population distribution. We have reviewed statistical methods that deal with this bias, particularly in the context of CoVID-19.