Genetic architecture of host proteins interacting with SARS-CoV-2 - July 2020
- Funded by UK Research and Innovation (UKRI)
- Total publications:0 publications
Grant number: C19-IUC-503
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Key facts
Disease
COVID-19Funder
UK Research and Innovation (UKRI)Principal Investigator
Dr. Claudia LangenbergResearch Location
United KingdomLead Research Institution
MRC Epidemiology UnitResearch Priority Alignment
N/A
Research Category
Clinical characterisation and management
Research Subcategory
Prognostic factors for disease severity
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
A team led by Unit researcher Dr Claudia Langenberg has published in Omicscience summary statistics for large-scale genomic and plasma proteomic data from over 10,000 individuals to characterise genetic architecture of host proteins reported to interact with SARS-CoV-2. This accompanies the submission of the paper "Genetic architecture of host proteins interacting with SARS-CoV" which is available on BioRxiv. The summary statistics freely available without restrictions, and include an interactive matrix and annotations for all protein targets and cis-associated genetic loci, as well as interactive tables with pGWAS summary statistics for individual SNPs, genes, or genetic regions from which results can be sorted, filtered, and exported.