TracK- Transmission of Coronavirus in Kids
- Funded by UK Research and Innovation (UKRI)
- Total publications:0 publications
Grant number: C19-IUC-513
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Key facts
Disease
COVID-19Funder
UK Research and Innovation (UKRI)Principal Investigator
Prof. Shiranee SriskandanResearch Location
United KingdomLead Research Institution
MRC Centre for Molecular Bacteriology and Infection at Imperial College LondonResearch Priority Alignment
N/A
Research Category
Epidemiological studies
Research Subcategory
Disease transmission dynamics
Special Interest Tags
N/A
Study Type
Clinical
Clinical Trial Details
Not applicable
Broad Policy Alignment
Pending
Age Group
Adolescent (13 years to 17 years)Adults (18 and older)Children (1 year to 12 years)
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
To refine our understanding of COVID-19 transmission and predict impact of different public health interventions, we have adapted an existing study of scarlet fever transmission in schools, to understand more about transmission of SARS-CoV2 between children and between children and adults. In contrast to adults, syndromic surveillance for COVID-19 in children is not helpful, as disease is largely asymptomatic. Sequential intensive testing of oral/nasopharyngeal samples is the ideal method to quantify or rule out transmission events, since we do not at present know if seroconversion is a reliable marker of exposure in asymptomatic children. Exploiting statutory notification systems, the study will explore the events that follow when a child is diagnosed with SARS-CoV2, both in the child, the environment around the child, and their contacts from school, and at home. Through a sequence of individual school cohort studies, we are using intense longitudinal sampling of children and the environment to address the following questions :1. Do symptomatic or asymptomatic children transmit the virus to each other or to adults in schools or household? Or are adults more likely to be the source of infection in children? 1. Do symptomatic or asymptomatic children transmit the virus to each other or to adults in schools or household? Or are adults more likely to be the source of infection in children?