TracK- Transmission of Coronavirus in Kids

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:0 publications

Grant number: C19-IUC-513

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Key facts

  • Disease

    COVID-19
  • Funder

    UK Research and Innovation (UKRI)
  • Principal Investigator

    Prof. Shiranee Sriskandan
  • Research Location

    United Kingdom
  • Lead Research Institution

    MRC Centre for Molecular Bacteriology and Infection at Imperial College London
  • Research Priority Alignment

    N/A
  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease transmission dynamics

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Adolescent (13 years to 17 years)Adults (18 and older)Children (1 year to 12 years)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

To refine our understanding of COVID-19 transmission and predict impact of different public health interventions, we have adapted an existing study of scarlet fever transmission in schools, to understand more about  transmission of SARS-CoV2 between children and between children and adults.  In contrast to adults, syndromic surveillance for COVID-19 in children is not helpful, as disease is largely asymptomatic. Sequential intensive testing of oral/nasopharyngeal samples is the ideal method to quantify or rule out transmission events, since we do not at present know if seroconversion is a reliable marker of exposure in asymptomatic children.   Exploiting statutory notification systems, the study will explore the events that follow when a child is diagnosed with SARS-CoV2, both in the child, the environment around the child, and their contacts from school, and at home. Through a sequence of individual school cohort studies, we are using intense longitudinal sampling of children and the environment to address the following questions :1. Do symptomatic or asymptomatic children transmit the virus to each other or to adults in schools or household? Or are adults more likely to be the source of infection in children? 1. Do symptomatic or asymptomatic children transmit the virus to each other or to adults in schools or household? Or are adults more likely to be the source of infection in children?