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Understanding the immunomodulatory effects of BCG on subsequent exposure to SARS-CoV2

  • Funded by Elizabeth Blackwell Institute for Health Research
  • Total publications:0 publications
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Key facts

  • Disease

    COVID-19

  • Funder

    Elizabeth Blackwell Institute for Health Research

  • Principal Investigator

    Unspecified Darryl Hill

  • Research Location

    United Kingdom

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The overarching objective of this project is to establish relevant cell culture models to evaluate the influence of immune modulation on infection by SARS-CoV-2. Large trials of BCG vaccine are being planned including UK for putative broad anti-infection effects perhaps including COVID. This research will test whether BCG vaccine immunomodulation alters the subsequent cellular response to SARS-CoV-2 using air liquid interface models.