Return to homepagePandemic Pact

Hyperinflammation and immunity in COVID-19

  • Funded by Elizabeth Blackwell Institute for Health Research
  • Total publications:1000 publications

Grant number: N/A

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Key facts

  • Disease

    COVID-19

  • start year

    -99

  • Known Financial Commitments (USD)

    $0

  • Funder

    Elizabeth Blackwell Institute for Health Research

  • Principal Investigator

    Laura Rivino

  • Research Location

    United Kingdom

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Establishing a robust and safe immunophenotyping methodology. This project aims to establish tools for the in-depth analysis of the activation/functionality of innate and adaptive immune cells in human blood, with the aim of subsequently applying these tools to probe immune cell activation in COVID-19 patients and define immune subsets driving the cytokine storm and biomarkers associated with immunopathology/immune protection.

Publicationslinked via Europe PMC

Last Updated:2 days ago

View all publications at Europe PMC

The Skills to Manage Pain Randomized Trial: Results of Antiretroviral Therapy Adherence, HIV Primary Care Retention, and Virologic Suppression Outcomes.

A reanalysis of population dynamics in the Casas Grandes region of Northern Mexico using mitochondrial DNA.

Action painting under spectroscopic light: Excited-state exchange interactions behind the vibrant blue in Jackson Pollock's <i>Number 1A, 1948</i>.

Improving the efficacy of anti-SSEA4 antibody in pancreatic cancer immunotherapy with glyco-optimization and immune checkpoint blockade.

Clenbuterol induces lean mass and muscle protein accretion, but attenuates cardiorespiratory fitness and desensitizes muscle β<sub>2</sub>-adrenergic signalling.

Posttranscriptional control of the B cell receptor by HuR is essential for innate B cell maintenance and function.

Five-year results of the SCENT trial with Surpass flow diverters to treat large or giant wide-neck aneurysms.

Peritumoral macrophages recruit eosinophils to promote antitumor immune responses in breast cancer.

Intention judgments are not a reliable measure of intuitive preferences.