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In silico screening for approved drug repurposing for COVID-19 using BUDE

  • Funded by Elizabeth Blackwell Institute for Health Research
  • Total publications:0 publications
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Key facts

  • Disease

    COVID-19

  • Start & end year

    N/A

  • Funder

    Elizabeth Blackwell Institute for Health Research

  • Principal Investigator

    James Spencer

  • Research Location

    United Kingdom

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Prophylactic use of treatments

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

This work will identify the most promising potential treatments for coronavirus infection from existing drugs, providing possible new avenues for patient treatment. Rapid progress establishing the atomic structures of some key coronavirus components now makes it possible to use computer-based methods to identify existing drugs that may interact with the virus and block its multiplication in infected cells. This project uses the Bristol University Docking Engine (BUDE) and the University's excellent High Performance Computing (HPC) facilities, to test databases of approved drugs against coronavirus targets.