SBIR Phase II: Remote Monitoring of Patients in Respiratory Distress

  • Funded by National Science Foundation (NSF)
  • Total publications:0 publications

Grant number: 2136554

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2022
    2023
  • Known Financial Commitments (USD)

    $1,000,000
  • Funder

    National Science Foundation (NSF)
  • Principal Investigator

    Alireza Akhbardeh
  • Research Location

    United States of America
  • Lead Research Institution

    CEREVU MEDICAL INC
  • Research Priority Alignment

    N/A
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Supportive care, processes of care and management

  • Special Interest Tags

    Digital Health

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to advance a real-time assessment system for patients at risk of respiratory distress. The goal is to monitor these patients and avoid hospital admissions or re-admissions for previously discharged patients. The first envisioned application is monitoring of Chronic Obstructive Pulmonary Disease (COPD), for which there is no cure - but the disease can be managed with diligent surveillance. The envisioned remote patient monitoring system will enhance patient care and outcomes by providing early warning of COPD flare-ups, thus reducing the need for emergency hospital visits and admissions. This system will provide healthcare workers and caregivers added time to implement protocols, such as inhaler-based drug delivery, thus reducing critical events for COPD, as well as COVID-19, asthma, pneumonia, and other respiratory illnesses.

This Small Business Innovation Research (SBIR) Phase II project is to develop a reusable device monitoring biomarkers of nociceptive pain, dyspnea, and coughing dynamics, along with traditional vital sign measurements. The project will develop a reusable device with a rechargeable battery and replaceable adhesives for prolonged use during the duration of the monitoring period. Additionally, the user interface will be optimized for the display of pertinent symptoms to the patient, caregivers, and medical personnel providing remote care from a centralized monitoring center. The efficient sharing of continuous changes in patient status will allow for the most effective personalized treatment. The project will develop a system with appropriate cybersecurity protocols.

This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.