New insights into children and young people's mental health derived from the interaction between the family ecosystem and the COVID-19 pandemic

Grant number: 224243/Z/21/Z

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2022
    2028
  • Known Financial Commitments (USD)

    $904,111.62
  • Funder

    Wellcome Trust
  • Principal Investigator

    Dr. Matthias Pierce
  • Research Location

    United Kingdom
  • Lead Research Institution

    University of Manchester
  • Research Priority Alignment

    N/A
  • Research Category

    Secondary impacts of disease, response & control measures

  • Research Subcategory

    Indirect health impacts

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Adolescent (13 years to 17 years)Children (1 year to 12 years)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Children and young people's (CYP's) mental health is an urgent priority. Dramatic, socio-economic changes following the COVID-19 pandemic has already disproportionately affected families, and with economic uncertainty, further shocks are expected. This fellowship shall use epidemiology, biostatistics, causal inference and machine learning applied to high-quality psychiatric surveys to investigate how changes to the family 'ecosystem' affects CYP mental health. The first goal is to describe typical family ecosystems and assess CYP mental health in each. The second goal will be to conduct first network analysis of mental health symptoms within families using graphical networks. The third goal will be to estimate the effect of acute changes from the pandemic (e.g. school closures) on CYP mental health. Finally, longer term changes to the family ecosystem will be determined, then analysed to assess their effect on CYP. For the latter two, I shall use causal mediation analysis to determine modifiable determinants of mental health and interaction analyses to determine which children are vulnerable, and what modifiable factors could create resilience. A website disseminating findings and provided a children's mental health dashboard shall be co-created with a CYP advisory group.

Publicationslinked via Europe PMC

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5-year mental health outcomes for children and adolescents presenting with psychiatric symptoms to general practitioners in England: a retrospective cohort study.

Substantially more children receiving antidepressants see a specialist than reported by Jack et al.

Changes to healthcare utilisation and symptoms for common mental health problems over the first 21 months of the COVID-19 pandemic: parallel analyses of electronic health records and survey data in England.