Can we develop a "cognitive vaccine" for intrusive memories of traumatic events from working in the COVID-19 pandemic? A novel and brief intervention to support ICU staff
- Funded by Wellcome Trust
- Total publications:15 publications
Grant number: 223016/Z/21/Z
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Key facts
Disease
COVID-19Start & end year
20212023Known Financial Commitments (USD)
$1,243,101.47Funder
Wellcome TrustPrincipal Investigator
Prof. Emily HolmesResearch Location
United KingdomLead Research Institution
P1vital Products LtdResearch Priority Alignment
N/A
Research Category
Secondary impacts of disease, response & control measures
Research Subcategory
Indirect health impacts
Special Interest Tags
Digital Health
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Adults (18 and older)
Vulnerable Population
Unspecified
Occupations of Interest
Hospital personnel
Abstract
Intensive care unit (ICU) staff face repeated exposure to traumatic work-related events and have reported high levels of posttraumatic symptoms during the pandemic. Novel, scalable and preventative interventions are required. We are developing a "cognitive vaccine" approach for ICU staff against one key symptom - intrusive memories of traumatic events. These are unwanted, distressing and disrupt functioning. Our novel, brief gameplay intervention is repeatable, flexible, non-stigmatising, scalable, and driven by mental health science. This digital intervention is guided by an initial session of psychologist support, then self-administered; delivered same day or months post-trauma, suitable for repeated trauma exposure, fits with busy lives of ICU staff, without discussing trauma detail. Part 1 uses a Bayesian design to optimise and co-develop procedures with ICU professionals and move at speed under pandemic conditions, allowing limited rollout (guided-version) in these unprecedented times. Part 2 uses a pragmatic RCT (three arms: guided/non-guided/attention-control) testing clinical effectiveness and acceptability to inform clinical practice. If the non-guided intervention is effective (i.e. no psychologist support) it will accelerate the speed of rollout. Meanwhile through global mental health workshops with stakeholder communities we seek to understand the views of various communities worldwide regarding implementation of this novel intervention form.
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