COVIGRO: Impact of COVID-19 and the vaccine against SARS-CoV-2 on the development of the placenta and the fetus

Google translate: Scientific data regarding the impact of COVID-19 on pregnancy is limited but suggests an increase in complications such as premature birth and preeclampsia. At the same time, scientific data are limited regarding the effectiveness of the COVID-19 vaccine given during pregnancy and whether gestational age can influence its effectiveness and/or impact on the outcome of the pregnancy. We will compare two cohorts of pregnant women, one recruited before the pandemic (2017-2018) and one recruited during the 2020-2021 pandemic. Using blood samples collected at different times of pregnancy, and using a questionnaire, we will be able to establish if the patient has been infected with COVID-19 and if she has received the vaccine. We will assess the effect of COVID-19 on placental development and fetal development, as well as the rate of complications. We will finally assess whether the vaccine received during pregnancy is as effective as the vaccine received before or after pregnancy.]