RECOVERY/Phase 2 Therapeutic Trials Reconfiguration

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:15 publications

Grant number: MC_PC_20062

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2023
  • Known Financial Commitments (USD)

    $21,868,820.56
  • Funder

    UK Research and Innovation (UKRI)
  • Principal Investigator

    Professor Martin J Landray
  • Research Location

    United Kingdom
  • Lead Research Institution

    University of Oxford
  • Research Priority Alignment

    N/A
  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Phase 2 clinical trial

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Clinical Trial, Phase II

  • Broad Policy Alignment

    Pending

  • Age Group

    Adults (18 and older)

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The RECOVERY trial is jointly funded by the NIHR and UK Research and Innovation (UKRI), with research delivery supported by the NIHR's Clinical Research Network at 176 hospital sites across the UK. The trial is being coordinated by researchers at the University of Oxford, which acts as the sponsor for the research. This award is jointly funded (50:50) between the UKRI and the NIHR. The figure displayed is the total award amount of the two funders combined, with each partner contributing equally towards the project. With this support, to date the trial has recruited over 12,000 participants - making it the world's largest trial of potential COVID-19 treatments. RECOVERY/Phase 2 Therapeutic Trials Reconfiguration also known as Recovery+ is additional support to continue the work of the initial RECOVERY trial titled COVID-19: multi-arm, multi stage adaptive clinical trial (CoV-MAMS) - MC_PC_19056.

Publicationslinked via Europe PMC

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A Pragmatic Randomized Feasibility Trial of Influenza Vaccines.

Establishing COVID-19 trials at scale and pace: Experience from the RECOVERY trial.

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.

Feasibility of randomizing Danish citizens aged 65-79 years to high-dose quadrivalent influenza vaccine vs. standard-dose quadrivalent influenza vaccine in a pragmatic registry-based setting: rationale and design of the DANFLU-1 Trial.

Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis.

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial.

Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study.

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19.