AI-based chest CT analysis enabling rapid COVID diagnosis and prognosis

Grant number: 101016131

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2023
  • Known Financial Commitments (USD)

    $3,807,228
  • Funder

    European Commission
  • Principal Investigator

    SMEETS Dirk
  • Research Location

    Belgium
  • Lead Research Institution

    ICOMETRIX NV
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

This icovid project is the continuation of the pro bono icovid initiative that developed the CE-marked and FDA permitted AI-based CT analysis software, icolung, and made it available in over 65 hospitals worldwide. The icovid project aims to improve the software making it of greater value as the clinical needs evolve, validating it in renowned academic centers and deploying it at large-scale across Europe. icolung is expected to have a significant societal impact by increasing confidence when making a CT diagnosis and providing accurate quantification of disease and prognostic information in patients with suspected COVID-19 disease. Importantly, even in a low prevalence setting icolung may have a much higher sensitivity and a comparable specificity for the diagnosis compared to the RT-PCR testing used currently. Identifying infected patients earlier will reduce the risk of further contamination and allows the right patient management to start earlier. icolung also predicts the risk of developing severe COVID-19 disease for which ICU admission and mechanical ventilation are required, allowing optimization of patient care. This project will significantly strengthen the position of two European SMEs in the rapidly growing market of AI in healthcare. One of them is coordinating the project and the consortium involved, enabling quick responses in a rapidly changing environment. The consortium builds further on existing organic collaboration and contains world-renowned experts of which multiple are part of the Executive Committee of the European Society of Thoracic Imaging.

Publicationslinked via Europe PMC

Last Updated:43 minutes ago

View all publications at Europe PMC

The Role of Imaging in the Detection of Non-COVID-19 Pathologies during the Massive Screening of the First Pandemic Wave.

Limitations of Only Reporting the Odds Ratio in the Age of Precision Medicine: A Deterministic Simulation Study.

Knowledge Graphs for COVID-19: An Exploratory Review of the Current Landscape.