Return to homepagePandemic Pact

rapiD and secuRe AI imaging based diaGnosis, stratification, fOllow-up, and preparedness for coronavirus paNdemics.

Grant number: 101005122

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Key facts

  • Disease

    Unspecified
  • Start & end year

    2020
    2024
  • Known Financial Commitments (USD)

    $13,430,724.6
  • Funder

    European Commission
  • Principal Investigator

    LAMBIN Philippe
  • Research Location

    Netherlands
  • Lead Research Institution

    UNIVERSITEIT MAASTRICHT
  • Research Priority Alignment

    N/A
  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease surveillance & mapping

  • Special Interest Tags

    Data Management and Data Sharing

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

In this project, a multinational consortium of high-tech SMEs, academic research institutes, biotech and pharma partners, affiliated patient-centred organisations and professional societies will achieve a multi-faceted diagnostic and prognostic platform and a precision medicine approach. This consortium will together realize a patient empowerment centred decision support system that will enable multiple stakeholders to participate in improved and more rapid diagnosis and prognosis, as well as the potential of precision medicine for accelerated development of new therapies. Citizens and patients will be empowered to contribute to the efficient planning and usage of resources. The project will begin by rapidly delivering a nomogram. Data from the Chinese epidemic will be used to validate and further optimise a European scalable radiological diagnosis/prognosis solution. Existing and new data and sample collection efforts will be used to perform molecular profiling, which - using advanced AI techniques will be shaped into a precision medicine approach. These initial outputs will undergo further enhancement and assessment to evaluate the value they add to the development of a decision support system. The entire effort will be supported by the deployment of a federated machine learning system that will allow for the GDPR compliant use of multinational data resources. The various iterations of the decision support system and the federated machine learning system will be made available to other coronavirus initiatives with the intent to develop a stakeholder community that forms the basis for a highly efficient innovation ecosystem. Our proposed study will be one of the first to develop innovative machine learning, and clinical procedure improvement that will potentially make a huge socio-economic impact for the coronavirus outbreak.

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NAD+ reverses Alzheimer's neurological deficits via regulating differential alternative RNA splicing of EVA1C.

Confounder-aware foundation modeling for accurate phenotype profiling in cell imaging.