Versatile Emerging infectious disease Observatory

Grant number: 874735

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Key facts

  • Disease

    Disease X
  • Start & end year

    2020
    2024
  • Known Financial Commitments (USD)

    $20,292,592.32
  • Funder

    European Commission
  • Principal Investigator

    SKIBY Jeffrey
  • Research Location

    Netherlands
  • Lead Research Institution

    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
  • Research Priority Alignment

    N/A
  • Research Category

    13
  • Research Subcategory

    N/A
  • Special Interest Tags

    Data Management and Data Sharing
  • Study Type

    Not applicable
  • Clinical Trial Details

    N/A
  • Broad Policy Alignment

    Pending
  • Age Group

    Not Applicable
  • Vulnerable Population

    Not applicable
  • Occupations of Interest

    Not applicable

Abstract

Our vision is to establish a Versatile forecasting, nowcasting, and tracking system (VEO) serving as an interactive observatory for the generation and distribution of high quality actionable information for evidence-based early warning, risk assessment and monitoring of Emerging Infectious Diseases and Antimicrobial resistance by public health actors and researchers in the One-Health domain.VEO will be built by an iterative process between data science and technology experts, disease experts from public health and academia, social scientists, and citizen scientists. The VEO data platform will support mining, sharing, integration, presentation and analysis of traditional and novel 'ÄòBio data'Äô with a range of 'ÄúContextual data'Äù, integrating publicly available and confidential data. The VEO analytical platform will support data-intensive interdisciplinary collaboration of geographically distributed international teams, co-creation of novel advanced analytical solutions, and involving citizen scientists through crowdsourcing of specific challenges. In addition, we will develop workflows to integrate high density laboratory data (genomics, phenotyping, immunomics) into the VEO system and into risk assessments. The VEO system is (co)designed and tested through five complementary use case scenarios, reflecting main pathways of disease emergence, to attune developments to the needs of its intended users, and obtain proof-of-principle of utility, including ethical, legal and social implications.

214 Publications linked via Europe PMC

Shared viral burdens: Molecular evidence of Usutu virus infection and multi-arbovirus exposure in migrant and resident birds at wintering locations in Nigeria.

The Network of National COVID-19 Data Portals: public health equity through collaboration

Patterns of emergence and circulation of West Nile Virus in Algeria.

Proxy immunization enabling yellow fever vaccination after thymectomy.

Phylodynamic analyses reveal persistence and extensive intermixing of Usutu virus in the Netherlands.

Prioritization of antimicrobial resistance surveillance of gram-negative pathogens - a stacked modelling approach

First Usutu Virus Infection in an Asymptomatic Blood Donor in Greece.

Invasion dynamics of the disease vector Aedes japonicus in Spain.

Whole-genome prediction of bacterial pathogenic capacity on novel bacteria using protein language models with PathogenFinder2.