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Strengthening Environmental Surveillance to Advance Public Health Action

Grant number: 101103253

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Key facts

  • Disease

    N/A

  • Start & end year

    2023
    2026
  • Known Financial Commitments (USD)

    $5,651,691.42
  • Funder

    European Commission
  • Principal Investigator

    . Lood Rolf
  • Research Location

    N/A
  • Lead Research Institution

    LUNDS UNIVERSITET
  • Research Priority Alignment

    N/A
  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease surveillance & mapping

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The ODIN project aims at strengthening capacity for genomics and bioinformatics database management skills for generating, maintaining, and querying large genomic epidemiology data sets in sub-Saharan countries. To reach this goal, ODIN will develop a genomic surveillance system relying on environmental monitoring of major communicable disease agents and antimicrobial resistance in community wastewater and other environmental samples containing human and animal excreta. In a socially and ethically acceptable anonymous manner, environmental surveillance systems follow the trends in prevalence and may detect the outbreaks of communicable diseases in human communities and to convey this information to key stakeholders for the efficient implementation of data-driven public health policies. A strong and innovative aspect of this project is the combination of various semi-automatic bioinformatics tools for the processing and analysis of genomic epidemiology data, disseminated through a visual dashboard, providing means for timely public health interventions. The ODIN project implements the three pillars of the One Health framework: human health, animal health and the environment, which is crucial for communicable disease epidemiology in resource- and infrastructure-poor regions. Together with extensive training activities, ODIN implementation will result in a substantial strengthening in the capacity and infrastructure in sub-Saharan countries for genomic epidemiology. Networking and capacity building are an integrated part of the project activities and will comprise communication activities with stakeholders and training of MSc and PhD students. By its multi-disciplinary team, ODIN will contribute to setting up a sustainable model for how environmental surveillance systems can support the control of poverty-related and emerging/re-emerging infections in sub-Saharan Africa and promote the public health interventions targeting safe water supply and sanitation.

6 Publications linked via Europe PMC

Strengthening pathogen and antimicrobial resistance surveillance through environmental monitoring in sub-Saharan Africa: stakeholder perspectives.

Illuminating the Invisible: Green Fluorescent Protein as a Beacon for Antibiotic-Induced Phage Activity in Escherichia coli.

MultiStageSearch: An Iterative Workflow for Unbiased Taxonomic Analysis of Pathogens Using Proteogenomics.

Open-Source and FAIR Research Software for Proteomics.

Antimicrobial resistance in the Nordics: mapping existing surveillance systems and assessing the impact of COVID-19 using regression models.

Metaproteomics Beyond Databases: Addressing the Challenges and Potentials of De Novo Sequencing.