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to determine whether tissue resident memory T cells, which are found in the nasal cavity during SARS-CoV-2 infection, help limit disease severity and viral replication, and mediate vaccine-induced immunity

Grant number: INV-032575

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Key facts

  • Disease

    COVID-19

  • start year

    2021

  • Known Financial Commitments (USD)

    $100,000

  • Funder

    Gates Foundation

  • Principal Investigator

    N/A

  • Research Location

    Canada

  • Lead Research Institution

    University of Manitoba

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Not applicable

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

N/A

Publicationslinked via Europe PMC

Last Updated:2 days ago

View all publications at Europe PMC

Expansion of cytotoxic tissue-resident CD8+ T cells and CCR6+CD161+ CD4+ T cells in the nasal mucosa following mRNA COVID-19 vaccination.