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to test the ReFrame library in human lung cell line infected with SARS2

Grant number: INV-018479

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020

  • Known Financial Commitments (USD)

    $1,246,352

  • Funder

    Gates Foundation

  • Research Location

    United States of America

  • Lead Research Institution

    University of Pennsylvania

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

N/A

3 Publications linked via Europe PMC

Last Updated:4 days ago

View all publications at Europe PMC

Selective decay of interferon mRNAs controls antiviral immunity and innate memory.

Pressure to evade cell-autonomous innate sensing reveals interplay between mitophagy, IFN signaling, and SARS-CoV-2 evolution.

Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Tracking.