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Structure-guided stabilization of the SARS-CoV-2 spike protein for vaccines and diagnostics.

Grant number: INV-017592

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020

  • Known Financial Commitments (USD)

    $100,000

  • Funder

    Gates Foundation

  • Research Location

    United States of America

  • Lead Research Institution

    University of Texas at Austin

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    N/A

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

N/A

4 Publications linked via Europe PMC

Last Updated:4 days ago

View all publications at Europe PMC

Display of Native SARS-CoV-2 Spike on Mammalian Cells to Measure Antibody Affinity and ADCC.

Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses.

Rapid characterization of spike variants via mammalian cell surface display.

Expression and characterization of SARS-CoV-2 spike proteins.