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to enable access to samples from COVID-19 patients to support mAb discovery and identification of correlates of natural protection/disease severity.

Grant number: INV-016575

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020

  • Known Financial Commitments (USD)

    $95,000

  • Funder

    Gates Foundation

  • Research Location

    United States of America

  • Lead Research Institution

    University of Washington Foundation

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

N/A

5 Publications linked via Europe PMC

Last Updated:4 days ago

View all publications at Europe PMC

A multifaceted high-throughput assay for probing antigen-specific antibody-mediated primary monocyte phagocytosis and downstream functions.

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes.

A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy.

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection.

Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2.