NEC - Broadly Protective Coronavirus Vaccine

April 8, 2022; OSLO, Norway/ TOKYO, Japan: CEPI, the Coalition for Epidemic Preparedness Innovations, and NEC Corporation (NEC: TSE: 6701) today announced the latest funding award under CEPI's US$200m programme to advance the development of vaccines that provide broad protection against SARS-CoV-2 variants and other betacoronaviruses. CEPI will provide seed funding of up to US$4.8m to NEC OncoImmunity AS (NOI), a Norway-based subsidiary of NEC, which specializes in artificial intelligence-driven biotechnology, to support the initial development of broadly protective betacoronavirus vaccine candidates. NEC, through NOI, will lead a research consortium including the European Vaccine Initiative (EVI) and Oslo University Hospital to deliver a project which aims to establish preclinical proof of concept for a vaccine based on mRNA technology that protects against a broad range of betacoronaviruses. NEC will apply its experience and capabilities in artificial intelligence-powered design of immunogens to identify novel vaccine antigens with broad reactivity against betacoronaviruses. The lead antigens will be selected iteratively and validated in preclinical studies against known betacoronaviruses that already pose a significant epidemic or pandemic risk, such as SARS-CoV, SARS-CoV-2 & MERS-CoV. If this innovative approach is proven to be successful, it may also be applicable for developing vaccines against other pathogens in the CEPI portfolio, including 'ÄòDisease X' - unknown pathogens with pandemic potential that have yet to emerge. CEPI is committed to the principle of equitable access to the vaccines it funds. Under the terms of the funding agreement, NEC has committed to achieving equitable access to the outputs of this project, in line with CEPI's Equitable Access Policy.