BULITA - The multifunctional bunyavirus L protein as an inhibitor target

  • Funded by Bundesministerium für Bildung und Forschung [German Federal Ministry of Education and Research] (BMBF)
  • Total publications:8 publications

Grant number: 01KI2019

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Key facts

  • Disease

    Unspecified, Unspecified
  • Start & end year

    2020
    2025
  • Known Financial Commitments (USD)

    $2,430,231.07
  • Funder

    Bundesministerium für Bildung und Forschung [German Federal Ministry of Education and Research] (BMBF)
  • Principal Investigator

    N/A

  • Research Location

    Germany
  • Lead Research Institution

    Bernhard-Nocht-Institut für Tropenmedizin (BNITM)
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    N/A

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Publicationslinked via Europe PMC

Last Updated:41 minutes ago

View all publications at Europe PMC

Structural snapshots of phenuivirus cap-snatching and transcription.

Limited high-throughput screening compatibility of the phenuivirus cap-binding domain.

RNA to Rule Them All: Critical Steps in Lassa Virus Ribonucleoparticle Assembly and Recruitment.

Structural and functional characterization of the Sin Nombre virus L protein.

A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells.

Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.

The mechanism of genome replication and transcription in bunyaviruses.

Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.