MADLID - Machine Learning Driven Liquid Biopsy Biomarker Discovery Platform

  • Funded by Swiss National Science Foundation (SNSF)
  • Total publications:2 publications

Grant number: 221565

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2023
    2024
  • Known Financial Commitments (USD)

    $144,187.7
  • Funder

    Swiss National Science Foundation (SNSF)
  • Principal Investigator

    Gurtner Jean-Luc
  • Research Location

    N/A
  • Lead Research Institution

    N/A
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Liquid biopsies-derived biomarkers have shown robust and promising efficacy for diagnosing and monitoring various diseases in a minimally invasive manner as we have seen in recent disease pandemics such as COVID-19 and cancer. However, sensitivity and specificity are one of the biggest issues associated with the current state-of-the-art approaches based on the detection of cell-free biomarkers such as nucleic acids, cytokines, and soluble antibodies. These issues are critical hurdles for physicians to fully harness the benefits of liquid biopsies in their diagnostics and treatment decisions. To tackle this, our novel discovery platform applies advanced machine learning to analyze tissues-specific extracellular vesicles (EVs) in our body to unleash the maximum potential of liquid biopsies diagnostics, real-time disease monitoring, and advanced artificial intelligence to enable reliable and personalized health monitoring and treatments.

Publicationslinked via Europe PMC

Last Updated:39 minutes ago

View all publications at Europe PMC

Intercellular Epigenomic Signalling via Extracellular Vesicles During B Cell Maturation.

Assessing Extracellular Vesicles in Human Biofluids Using Flow-Based Analyzers.