Contribution to NordForsk's call for Nordic health data research project on COVID-19 | Pandemic PACT Tracker

Key facts

Disease
COVID-19
Start & end year
2020
Known Financial Commitments (USD)
$598,617.57
Funder
The Research Council of Norway (RCN)
Principal Investigator
Mikael Heimonen
Research Location
Norway
Lead Research Institution
NORDFORSK
Research Priority Alignment
N/A

Research Category
14
Research Subcategory
N/A
Special Interest Tags
N/A
Study Type
Unspecified
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable

Abstract

Publicationslinked via Europe PMC

Last Updated:39 minutes ago

View all publications at Europe PMC

Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases.

1,6-epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease.

Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.

Structural Insights into Pixatimod (PG545) Inhibition of Heparanase, a Key Enzyme in Cancer and Viral Infections.

Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents.

An Epoxide Intermediate in Glycosidase Catalysis.

Synthetic and Crystallographic Insight into Exploiting sp² Hybridization in the Development of α-l-Fucosidase Inhibitors.

Functionalized Cyclophellitols Are Selective Glucocerebrosidase Inhibitors and Induce a Bona Fide Neuropathic Gaucher Model in Zebrafish.

Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.