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Targeting neuropilin in SARS-Cov-2 neuronal uptake and transport

  • Funded by National Health and Medical Research Council (NHMRC)
  • Total publications:0 publications

Grant number: GA204244

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2022
    2025

  • Known Financial Commitments (USD)

    $652,185.66

  • Funder

    National Health and Medical Research Council (NHMRC)

  • Research Location

    Australia

  • Lead Research Institution

    The University of Queensland

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

COVID-19 is associated with a variety of neurological symptoms, ranging from a transient loss of smell and taste to headaches to severe ischaemic damage in fatal cases. The long-term consequences of potential interactions of the causative virus, SARS-CoV-2, with brain cells are currently unknown but could be linked to intractable neuronal degeneration as previously found with the 1918 influenza pandemic. We will investigate the uptake and transport of the virus and find ways to block infection.