Excess mortality during the COVID-19 pandemic in the Netherlands in vaccinated and non-vaccinated individuals in the context of medical history, frailty and sociodemographic factors

In this project we investigate the role of COVID-19 vaccinations in excess mortality. We take into account important factors such as people's medical history. We use data from electronic patient files of general practitioners of approximately 8% of Dutch people. We link this data at patient level to data about COVID-19 vaccination, COVID-19 testing, causes of death and personal data. We compare the observed mortality in 2021 among people who have and people who have not been vaccinated with the expected mortality. We distinguish between type of vaccine, number of vaccinations, medical history, vulnerability (in the elderly) and social demographic characteristics. The results of this study are important in the evaluation of (the safety of) vaccines and can be used for decisions regarding future vaccination policy and for information provision about vaccination.