Covid-19 lockdown and its impact on mortality rate in Alzheimer's - the CORAL project

The patients who attended the memory clinic during the Corona lockdown have been compared with historical control patients. A higher risk of mortality is seen in memory clinic patients who have experienced the pandemic, especially patients with dementia and especially patients who were admitted to a nursing home. When comparing causes of death between pandemic patients and historical controls, we see a higher mortality rate in pandemic patients for death due to COVID-19 infection and other causes of death (including external cause of death). A lower mortality rate in pandemic patients is seen for death from neoplasms and cardiovascular diseases. Only the difference between pandemic patients and historical controls for death from COVID-19 infection is significant. We do not have an estimate of healthcare use during the entire COVID-19 pandemic. Nevertheless, we analyzed healthcare costs from 2015-2020, which showed that our pandemic patients had significantly lower healthcare costs in 2020 compared to historical controls in 2018.