COVID19 Outcomes in Older People - the COOP study

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:24 publications

Grant number: 10430102110005

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2021
    2024
  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)
  • Principal Investigator

    dr SP. prof Mooijaart
  • Research Location

    Netherlands
  • Lead Research Institution

    Leids Universitair Medisch Centrum
  • Research Priority Alignment

    N/A
  • Research Category

    Clinical characterisation and management
  • Research Subcategory

    Prognostic factors for disease severity
  • Special Interest Tags

    N/A
  • Study Type

    Unspecified
  • Clinical Trial Details

    N/A
  • Broad Policy Alignment

    Pending
  • Age Group

    Older adults (65 and older)
  • Vulnerable Population

    Unspecified
  • Occupations of Interest

    Unspecified

Abstract

More than 90% of all deaths from COVID-19 occur in patients aged 70 years and older and functional decline is common. The elderly are very different in terms of vitality and vulnerability. Goal Customized treatment starts with a good assessment of the prognosis and knowledge about the disease, but much is still unknown. Does frailty predict the short- and long-term consequences of COVID-19 in older people? How do biological aging and vulnerability play a role in mortality or recovery? What are goals that are important for older people when making treatment decisions for acute serious conditions? Research design In the COOP study, all necessary professionals and elderly people work together to optimize the consequences of elderly people with COVID-19 through thorough scientific research. By using the many Dutch data previously collected in elderly people with COVID-19 in primary care, at home, in hospitals and in nursing homes, the results will become available quickly.

24 Publications linked via Europe PMC

Dynamic indicators of resilience in COVID-19 patients: a comprehensive analysis of heart rate dynamics.

Perceptions, motivations, needs and experiences of geriatricians with regard to research and research consortia.

Associations between metabolomic scores and clinical outcomes in hospitalized COVID-19 patients.

Regional differences in triage decisions affect hospital mortality among frail COVID-19 patients in the COvid MEdicaTion study.

Validation of the acutely presenting older patient screener for short term mortality prediction in older patients hospitalized for COVID-19.

A qualitative study regarding older people's goals of care in relation to frailty status: finding meaning in 'smaller things' in life.

The influence of the dynamic context of the pandemic on the predictive performance of mortality predictions over time in older patients hospitalized for COVID-19.

Continuous Monitoring Enables Dynamic Biomarkers to Assess Resilience in Acute COVID-19 Patients.

Charlson comorbidity index has no incremental value for mortality risk prediction in nursing home residents with COVID-19 disease.