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Persistent complaints after COVID-19 infection: epidemiology, pathophysiology, prediction, and communication, the CORona Follow Up (CORFU) study

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:0 publications

Grant number: 1.04303E+13

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2021
    2023

  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)

  • Principal Investigator

    dr C. Ghossein MD PhD

  • Research Location

    Netherlands

  • Lead Research Institution

    Maastricht University

  • Research Priority Alignment

    N/A

  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease surveillance & mapping

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Project CORona Follow Up (CORFU) investigated persistent complaints after COVID-19 infection. CORFU bundles 6 national COVID-19 cohorts and 1 survey. The goals were to map post-COVID symptoms and their relationship with quality of life (QoL), develop a prediction model and investigate pathogenesis. At 24 months, 43% of participants with an infection at home, 65% of ward patients and 63% of intensive care patients, had post-COVID symptoms. Fatigue was most common. QoL did not differ between the Covid-19 patients, but it is lower than in people without previous COVID-19. Having at least one post-COVID symptom two years after infection can be predicted by gender, severity of initial infection, and other health conditions that existed before getting COVID-19. The results highlight the need for research into the underlying mechanisms and treatment options for patients with post-COVID symptoms.