CoLab-score and viability PCR for SARS-CoV-2: routine blood test algorithm proven by elimination of viable SARS-CoV-2 to identify patients in order to facilitate discharge and/or de-isolation
- Funded by Netherlands Organisation for Health Research and Development (ZonMW)
- Total publications:0 publications
Grant number: 1.04301E+13
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Key facts
Disease
COVID-19Start & end year
20212024Funder
Netherlands Organisation for Health Research and Development (ZonMW)Principal Investigator
SHM GorissenResearch Location
N/ALead Research Institution
Zuyderland Medisch CentrumResearch Priority Alignment
N/A
Research Category
Clinical characterisation and management
Research Subcategory
Prognostic factors for disease severity
Special Interest Tags
N/A
Study Type
Unspecified
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
Long-term occupancy of isolation rooms by COVID-19 patients leads to further pressure on regular non-COVID care. In addition, treating and caring for COVID-19 patients in isolation is associated with physical and psychological burden for the patient and healthcare staff. An algorithm has been developed that can calculate the so-called CoLab score based on the patient's age and about 10 standard blood values that are measured daily in the ICU. The researchers of this study want to investigate whether the CoLab score can be used to release COVID-19 patients from isolation earlier and safely. Research design The CoLab score will be compared with the current standard PCR test and a recently developed PCR test (viability PCR) that can exclude the presence of infectious virus particles. In this way, the researchers can demonstrate that a patient with a normalized CoLab score is no longer contagious and can be safely removed from isolation.