CoLab-score and viability PCR for SARS-CoV-2: routine blood test algorithm proven by elimination of viable SARS-CoV-2 to identify patients in order to facilitate discharge and/or de-isolation

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:0 publications

Grant number: 1.04301E+13

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2021
    2024
  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)
  • Principal Investigator

    SHM Gorissen
  • Research Location

    N/A
  • Lead Research Institution

    Zuyderland Medisch Centrum
  • Research Priority Alignment

    N/A
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Prognostic factors for disease severity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

Long-term occupancy of isolation rooms by COVID-19 patients leads to further pressure on regular non-COVID care. In addition, treating and caring for COVID-19 patients in isolation is associated with physical and psychological burden for the patient and healthcare staff. An algorithm has been developed that can calculate the so-called CoLab score based on the patient's age and about 10 standard blood values ​​that are measured daily in the ICU. The researchers of this study want to investigate whether the CoLab score can be used to release COVID-19 patients from isolation earlier and safely. Research design The CoLab score will be compared with the current standard PCR test and a recently developed PCR test (viability PCR) that can exclude the presence of infectious virus particles. In this way, the researchers can demonstrate that a patient with a normalized CoLab score is no longer contagious and can be safely removed from isolation.