Sniffing out Covid: Perspective for patients with persisting loss of smell, towards better understanding and treatment.

In the past year, an estimated 2 out of 3 patients with a COVID-19 infection experienced loss of smell. For the majority, the sense of smell returns within a few weeks, but there are also patients whose complaints persist or who experience a disturbed sense of smell. These complaints have a major impact on daily life. In addition, not enough is known so far about the course and treatment options of loss of smell in COVID-19 patients. This study therefore investigates the natural course of anosmia (lack of sense of smell) in the context of COVID-19 and whether this can be beneficially influenced with (local) corticosteroids. Goal The aim of this study is to investigate the natural course of anosmia (lack of sense of smell) after a COVID-19 infection and whether this can be beneficially influenced with (local) corticosteroids. Research design Over the course of a year, the sense of smell and taste of a group of COVID-19 patients will be repeatedly measured and their influence on eating behavior and quality of life examined. The researchers are also investigating the effect of a change in smell on the brain. They are also conducting research into treatment options for loss of smell in COVID-19, with oral corticosteroids. With this they want to improve the care and prospects for this patient group and gain more knowledge about effective treatments.