Timing and sequence of vaccination against COVID-19 and Influenza (TACTIC)

Background and purpose It is currently uncertain how long the corona vaccinations protect against COVID-19. It may be necessary to give vulnerable people an annual booster of the corona vaccine before the winter season to provide them with lasting protection against COVID-19. Then there is also the annual flu shot, but it is unknown whether and how these vaccines influence each other. This study focuses on assessing the immune response and side effects after combined vaccination against COVID-19 and influenza in people ≥ 60 years of age. Research design In this study, 140 subjects aged ≥ 60 years receive a flu vaccine and corona vaccine at different times and sequences. Their blood is examined to see how their immune system responds to these vaccinations. Participants also keep track of how much they suffer from side effects. Expected results The researchers expect to provide a good picture of how corona and flu vaccinations can be given as efficiently, effectively and safely as possible.