COVID-19 and ischemic stroke - How to tame a dozing monster

Patients with COVID-19 pneumonia, especially if they are admitted to intensive care, can develop thrombotic complications, which can contribute to a more serious course of COVID-19 pneumonia. Pulmonary embolism (clot in the lung) is the most common complication, but cerebral infarctions can also occur. The hypothesis in this study is that these strokes may be caused by clotting activation and vessel wall inflammation, or that they are the result of a blood clot that travels from the leg or pelvic vessels through an open connection between the right and left sides of the heart into the cerebral vessels. ends up. Research and expected outcomes In three work packages, knowledge is obtained about: an accurate estimate of the occurrence of cerebral infarctions in COVID-19 ICU patients. the causes and consequences of cerebral infarctions based on imaging studies and laboratory determinations. the optimal prevention of cerebral infarctions by examining the effect of different treatments.