Clinical prediction models for COVID-19: development, international validation and use

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:0 publications

Grant number: 1.043E+13

Grant search

Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2021
  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)
  • Principal Investigator

    Dr ir D van Klaveren
  • Research Location

    N/A
  • Lead Research Institution

    Erasmus MC
  • Research Priority Alignment

    N/A
  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Prognostic factors for disease severity

  • Special Interest Tags

    N/A

  • Study Type

    Clinical

  • Clinical Trial Details

    Unspecified

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

For good care of COVID-19 patients, it is crucial to be able to estimate the expected course of their disease. For example: What is the probability that a patient will require intensive care (ICU)? What is the chance of death? Research In this study, a prediction model (https://mdmerasmusmc.shinyapps.io/COPE/ ) has been developed that provides answers to these questions upon admission to hospital. Data from almost 6,000 patients from four Dutch hospitals were used for this. Six easily measurable predictive factors have been used in the models, so that the model is easy to use. The model provided accurate predictions for more than 3,000 Dutch and 2,000 American patients in the second wave of the pandemic. Results Interviews with healthcare providers, patients and relatives showed that they see the value of these types of models when making decisions about optimal care for the patient. The models must then be available electronically and the predictions must be clearly communicated. View the scientific publication with the results of this research.