SARSLIVA and utility of saliva in diagnosis for wide scale testing, including viral and SARS-CoV-2 antibody detection in pre- and asymptomatic persons and follow-up of infections in COVID-19 patient; a house hold study
- Funded by Netherlands Organisation for Health Research and Development (ZonMW)
- Total publications:0 publications
Grant number: 1.043E+13
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Key facts
Disease
COVID-19Start & end year
20202022Funder
Netherlands Organisation for Health Research and Development (ZonMW)Principal Investigator
Dr SF. van LelyveldResearch Location
N/ALead Research Institution
Spaarne GasthuisResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Diagnostics
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Adults (18 and older)Children (1 year to 12 years)
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
High level of spread of the coronavirus within households - results of the SARSLIVA study A total of 85 households (326 adults and children) participated in the SARSLIVA study. The study lasted 6 weeks and participants collected saliva themselves at 10 times with a tube or, for the little ones, with a so-called 'sucking cotton ball'. The research team also collected a nasal swab, throat swab and a finger prick from the participants. The most important outcome of the SARSLIVA study is that a high degree of spread of the coronavirus within households was found due to the frequent collection of saliva in combination with swabs and blood collection to determine antibodies. In 88% of households where someone was infected with the coronavirus, one or more housemates also became infected. These results also show that taking saliva can be an attractive way to investigate the spread of the coronavirus.