RECoVERED

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:18 publications

Grant number: 10150062010002

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2020
    2021
  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)
  • Principal Investigator

    dr MD. Prof de Jong
  • Research Location

    N/A
  • Lead Research Institution

    Amsterdam UMC - locatie AMC
  • Research Priority Alignment

    N/A
  • Research Category

    Clinical characterisation and management
  • Research Subcategory

    Post acute and long term health consequences
  • Special Interest Tags

    N/A
  • Study Type

    Clinical
  • Clinical Trial Details

    Not applicable
  • Broad Policy Alignment

    Pending
  • Age Group

    Unspecified
  • Vulnerable Population

    Unspecified
  • Occupations of Interest

    Unspecified

Abstract

In the RECoVERED study, almost 350 patients with mild to severe Covid-19 are being followed long-term to better understand how the immune system against the virus develops and responds to vaccination after infection, what the risk is for long-term complaints ('long Covid'), what complaints these are and why they arise. Findings so far show that, due to built-up immunity after infection, a single vaccination produces an excellent antibody response, even better than after 2 vaccinations without a previous infection. It has also become clear that long-term complaints, especially fatigue and shortness of breath, are common after experiencing Covid-19, even after mild infections, but that the risk of this is greater the more serious the infection was. An extensive search is currently underway for possible causes of 'long covid' complaints using collected data and blood samples. Results from this will hopefully allow us to better combat the long-term effects of COVID-19. The RECoVERED study is carried out by Amsterdam UMC - location AMC, Erasmus MC and GGD Amsterdam. Read more on the Amsterdam UMC website . More information about research into corona and COVID-19 at www.zonmw.nl/coronaonderzoek

18 Publications linked via Europe PMC

Deep profiling of B cells responding to various pathogens uncovers compartments in IgG memory B cell and antibody-secreting lineages.

Inflammatory profiles are associated with long COVID up to 6 months after COVID-19 onset: A prospective cohort study of individuals with mild to critical COVID-19.

Determinants of epidemic size and the impacts of lulls in seasonal influenza virus circulation.

Aberrant neutrophil degranulation in hospitalized patients with COVID-19 partially remains for 6 months.

Two-year trajectories of COVID-19 symptoms and their association with illness perception: A prospective cohort study in Amsterdam, the Netherlands.

One-fourth of COVID-19 patients have an impaired pulmonary function after 12 months of disease onset.

Two-year trajectories of COVID-19 symptoms and their association with illness perception: A prospective cohort study in Amsterdam, the Netherlands

Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron.

Evolution of Coronavirus Disease 2019 (COVID-19) Symptoms During the First 12 Months After Illness Onset.