Malawi-Liverpool-Wellcome Trust COVID-19 Epidemic Preparedness

Key facts

Disease
COVID-19
Start & end year
2020
2021
Known Financial Commitments (USD)
$153,348.31
Funder
Wellcome Trust
Principal Investigator
Dr. Ben Morton
Research Location
United Kingdom
Lead Research Institution
Liverpool School of Tropical Medicine
Research Priority Alignment
N/A

Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Diagnostics
Special Interest Tags
N/A
Study Type
Not applicable
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable

Abstract

Malawi is at high risk of COVID-19 epidemic spread, the healthcare system is fragile and the population vulnerable to severe disease. This application proposes Malawi Liverpool Wellcome Trust Clinical Research Programme preparedness activities for epidemic COVID-19 disease. These are split into three work packages: 1) Diagnostic capacity and genomics surveillance; 2) Secondary care; 3) Epidemiology and control. Strategically, we have designed our activities to develop a platform for MLW to rapidly pivot into response mode to both support the healthcare system and deliver excellent research for current and future epidemic disease threats. Key goals for this proposal are: - Provide diagnostic capability in Malawi for the COVID-19 epidemic - Develop clinical and epidemiological tools to manage epidemic disease in Malawi

Publicationslinked via Europe PMC

Last Updated:38 minutes ago

View all publications at Europe PMC

Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international multi-centre prospective observational study.

Major adverse cardiovascular events (MACE) in patients with severe COVID-19 registered in the ISARIC WHO clinical characterization protocol: A prospective, multinational, observational study.

Different clinical features in Malawian outpatients presenting with COVID-19 prior to and during Omicron variant dominance: A prospective observational study.

Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19.

Authors
Kartsonaki C, Baillie JK, Barrio NG, Baruch J, Beane A, Blumberg L, Bozza F, Broadley T, Burrell A, Carson G, Citarella BW, Dagens A, Dankwa EA, Donnelly CA, Dunning J, Elotmani L, Escher M, Farshait N, Goffard JC, Gonçalves BP, Hall M, Hashmi M, Sim Lim Heng B, Ho A, Jassat W, Pedrera Jiménez M, Laouenan C, Lissauer S, Martin-Loeches I, Mentré F, Merson L, Morton B, Munblit D, Nekliudov NA, Nichol AD, Singh Oinam BC, Ong D, Panda PK, Petrovic M, Pritchard MG, Ramakrishnan N, Ramos GV, Roger C, Sandulescu O, Semple MG, Sharma P, Sigfrid L, Somers EC, Streinu-Cercel A, Taccone F, Vecham PK, Kumar Tirupakuzhi Vijayaraghavan B, Wei J, Wils EJ, Ci Wong X, Horby P, Rojek A, Olliaro PL, ISARIC Clinical Characterisation Group.
Publish Year
2023
Journal
International journal of epidemiology
DOI
10.1093/ije/dyad012

View at Europe PMC

Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity.

Authors
Marwali EM, Kekalih A, Yuliarto S, Wati DK, Rayhan M, Valerie IC, Cho HJ, Jassat W, Blumberg L, Masha M, Semple C, Swann OV, Kohns Vasconcelos M, Popielska J, Murthy S, Fowler RA, Guerguerian AM, Streinu-Cercel A, Pathmanathan MD, Rojek A, Kartsonaki C, Gonçalves BP, Citarella BW, Merson L, Olliaro PL, Dalton HJ, International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) Clinical Characterization Group Investigators.
Publish Year
2022
Journal
BMJ paediatrics open
DOI
10.1136/bmjpo-2022-001657