An Open Source Framework for Rift Valley Fever Forecasting

Grant number: 226061/Z/22/Z

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Key facts

  • Disease

    Rift Valley fever
  • Start & end year

    2022
    2027
  • Known Financial Commitments (USD)

    $600,204.71
  • Funder

    Wellcome Trust
  • Principal Investigator

    Dr. Noam Ross
  • Research Location

    United States of America
  • Lead Research Institution

    EcoHealth Alliance
  • Research Priority Alignment

    N/A
  • Research Category

    Infection prevention and control

  • Research Subcategory

    Restriction measures to prevent secondary transmission in communities

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Rift Valley Fever (RVF) is a complex disease with devastating public health and economic costs. It is transmitted directly from livestock to people and is maintained via mosquito transmission in livestock populations. As a zoonotic disease with a vector component, outbreaks of RVF are tightly linked to climatic and environmental conditions. Statistical modeling approaches have been developed to forecast RVF in Africa, but performance has been inconsistent across regions, with higher predictive accuracy in East Africa than in Southern Africa. Current continent-wide models, which use the Normalized Difference Vegetation Index (NDVI) to predict RVF activity, do not capture local attributes, such as livestock density and land cover, which may explain differing performance. We have assembled a team that includes local South Africa (RSA) government stakeholders, and co-created a tool for RSA that builds on previous work to create an RVF Early Warning System for RSA. Our goal is to package this new, open, locally customizable tool developed for RSA for deployment to other impacted regions. The intent is that end-users (farmers, farmer associations, others) would be forewarned when to vaccinate their livestock against RVF, a month to three months in advance of potential RVF activity.