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Genomic surveillance of infectious diseases in wastewater 2024-2025

  • Funded by State Secretariat for Education, Research, and Innovation SERI (Staatssekretariat für Bildung, Forschung und Innovation)
  • Total publications:0 publications

Grant number: 142006587

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Key facts

  • Disease

    COVID-19

  • start year

    2024

  • Known Financial Commitments (USD)

    $844,483.9

  • Funder

    State Secretariat for Education, Research, and Innovation SERI (Staatssekretariat für Bildung, Forschung und Innovation)

  • Principal Investigator

    Abteilung Übertragbare Krankheiten Sekretariat der

  • Research Location

    N/A

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen genomics, mutations and adaptations

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Continuous genomic monitoring in wastewater makes it possible to obtain a timely overview of the SARS-CoV-2 virus variants currently circulating in Switzerland. This makes it possible to identify virus variants that are resistant to vaccinations or medications or that lead to severe illnesses. In addition, their relative frequencies can be estimated. This is relevant in order to take early measures if necessary. Genomic monitoring includes:- sequencing of SARS-CoV-2 gene fragments in wastewater samples, - bioinformatic analysis of the raw sequence data to detect SARS-CoV-2 virus variants and their relative proportions, - testing the applicability of this methodology for other respiratory viruses.