Characterization of the atypical M2 protein of bat influenza A viruses

  • Funded by State Secretariat for Education, Research, and Innovation SERI (Staatssekretariat für Bildung, Forschung und Innovation)
  • Total publications:0 publications

Grant number: 7270245

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Key facts

  • Disease

    Other
  • Start & end year

    2020
    2023
  • Known Financial Commitments (USD)

    $524,035.56
  • Funder

    State Secretariat for Education, Research, and Innovation SERI (Staatssekretariat für Bildung, Forschung und Innovation)
  • Principal Investigator

    Gert Zimmer
  • Research Location

    N/A
  • Lead Research Institution

    N/A
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen morphology, shedding & natural history

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Project funded by the SNSF SNF | P3 research database | Project 189151The M2 protein is a small viral membrane protein that performs a variety of tasks in the replication cycle of influenza A viruses. The protein's conductivity for protons plays an important role in the introduction of the viral genome into the host cell. The cytoplasmic region of the protein, however, is important for virus maturation. This section of the M2 protein interacts with numerous cellular proteins whose role in virus maturation and release is still largely unclear.