Elaboration of prognostic measures and potential therapies based on severe cases of COVID-19 patients

The current project describes COVID-19 hospitalisations in Estonia during 2020, their treatment outcomes and investigates risk factors for severe disease. We will evaluate the treatment standard variety in different hospitals in Estonia. Genetic studies will hopefully provide the risk groups for COVID-19 disease acquisition. We plan to analyze the immune response dynamics of COVID-19 patients during and after hospitalization together with long term evaluation in Estonian cohort of patients. Effectiveness of convalescent plasma therapy in the treatment of COVID-19 patients will be evaluated. There are several different specialities included in the project: clinical medicine, epidemiology and biostatistics, immunology, virology and genetic experts of the University of Tartu. We will cooperate with all the COVID-19 treating hospitals in Estonia. This collaboration will hopefully provide the most important aspects to consider during infectious diseases outbreaks in the future.