H-NMR in solid state and complementary applications
- Funded by Estonian Research Council
- Total publications:4 publications
Grant number: PRG1832
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Key facts
Disease
COVID-19Start & end year
20232027Known Financial Commitments (USD)
$579,042Funder
Estonian Research CouncilPrincipal Investigator
Samoson, AgoResearch Location
EstoniaLead Research Institution
Tallinn University of TechnologyResearch Priority Alignment
N/A
Research Category
14
Research Subcategory
N/A
Special Interest Tags
Innovation
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
We shall custom-engineer MAS and metabolomics NMR and apply it on selected problems, notably Alzheimer's, Parkinson's, COVID, diabetes and cardiovascular conditions, fluor ion batteries, wood chemistry, also universal AI-assisted diagnostics and monitoring. We shall in particular focus on phytochemicals as the fastest and least harmful option to address acute health issues like SARS infection and neurodegenerative diseases. New hardware, based on fast mechanical spinning up to 15 Million RPM, electron spin polarization transfer (DNP), a sophisticated multi-axes sample rotation (DOR) and also 1.2GHz NMR magnets are expected to provide an unprecedented resolution and sensitivity in NMR, rendering it principally more helpful for a significantly wider range of material sciences and biomedical topics. In complex functional cases, the NMR will be arguably more informative and convenient than presently popular methods of plasmon resonance, CryoEM, X-ray or MS.
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