Determining customer benefits of reduced influenza and norovirus transmission, using sewage surveillance

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:1 publications

Grant number: 10050739

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Key facts

  • Disease

    COVID-19, Unspecified
  • Start & end year

    2023
    2024
  • Known Financial Commitments (USD)

    $59,971.9
  • Funder

    UK Research and Innovation (UKRI)
  • Principal Investigator

    Claire Trant
  • Research Location

    United Kingdom
  • Lead Research Institution

    UNTAP LTD
  • Research Priority Alignment

    N/A
  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease surveillance & mapping

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Untap is tackling one of the greatest challenges of our time, keeping our communities safe from viruses and infections. Currently viruses are only detected when an individual presents symptoms. Often, this is after viral transmission has already occurred. Influenza and norovirus were estimated to cost the UK economy 4% productivity loss in 2019; accounting for £ billions in lost revenue, and millions of infected individuals. Sewage surveillance is an incredible tool. It is used to measure the health of a community directly by their collective sewage. Humans shed viral RNA from day zero of infection, therefore this can be used to detect viruses pre-symptoms, and pre-transmission. Unlike lateral flow tests, which often have low participation rates, wastewater can provide broad coverage. However, the current state-of-the-art is manually collecting the sewage and analysing it in a laboratory. This analysis takes days, and costs up to £ thousands per sample. The cost and delay to the data has prevented sewage surveillance being carried out at a local scale. Untap have developed a prototype to detect COVID-19 in sewage of a community: onsite, automated, sewage surveillance. In this project we will develop this prototype to detect influenza and norovirus. This prototype will then be deployed long term at two sites, integrating the viral data into their day-to-day workflow. This will enable us to determine the customer benefits, both economic and intangible.

Publicationslinked via Europe PMC

Last Updated:38 minutes ago

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Near-source wastewater surveillance of SARS-CoV-2, norovirus, influenza virus and RSV across five different sites in the UK.