Influenza A virus evolution: Determining the key factors that influence emergence of influenza variants of animal and public health significance

  • Funded by UK Research and Innovation (UKRI)
  • Total publications:0 publications

Grant number: 2414134

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Key facts

  • Disease

    Unspecified
  • Start & end year

    2020
    2025
  • Known Financial Commitments (USD)

    $0
  • Funder

    UK Research and Innovation (UKRI)
  • Principal Investigator

    N/A

  • Research Location

    United Kingdom
  • Lead Research Institution

    Royal Veterinary College
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Pathogen genomics, mutations and adaptations

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Our research aims to understand the complex evolutionary pathways that result in the emergence of influenza virus variants that pose a threat to human and animal health. The project will identify viral and host factors (particularly in poultry and pigs) which determine the potential for emergence into new hosts and explore how this understanding can be used to implement effective control measures such as vaccination. We take an inter-disciplinary approach to One Health questions, by integrating surveillance, virology, ecology, and state-of-the-art antigenic and genetic computational analyses to understand pathogen evolution. Along with training and guidance, you will have flexibility to shape the project according to your interests.