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Affinity Reagents for the Immune System of Golden Hamster (for SARS-CoV-2 induced long-COVID disease)

  • Funded by National Institutes of Health (NIH)
  • Total publications:0 publications

Grant number: 75N93023C00035-0-9999-1

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2023
    2025

  • Known Financial Commitments (USD)

    $600,000

  • Funder

    National Institutes of Health (NIH)

  • Principal Investigator

    HONG QI

  • Research Location

    United States of America

  • Lead Research Institution

    QOOLABS, INC.

  • Research Priority Alignment

    N/A

  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

QooLabs proposes to generate high-affinity monoclonal antibodies against six immune cell targets of Syrian golden hamsters that are relevant to long-COVID research. Specifically, the Offeror proposes to produce recombinant proteins as immunogens for immunization of rabbits, to generate rabbit monoclonal antibodies using their proprietary method, and to validate the antibodies for use in long-COVID research in the hamster model for SARS-CoV-2.