Completion of ACTIV-2 Study

Key facts

Disease
COVID-19
Start & end year
2022
2024
Known Financial Commitments (USD)
$82,531,927
Funder
National Institutes of Health (NIH)
Principal Investigator
ANGEE GREER
Research Location
United States of America
Lead Research Institution
PPD DEVELOPMENT LP
Research Priority Alignment
N/A

Research Category
Therapeutics research, development and implementation
Research Subcategory
Clinical trial (unspecified trial phase)
Special Interest Tags
N/A
Study Type
Clinical
Clinical Trial Details
Unspecified
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified

NIAID is sponsoring a clinical research study on novel therapeutics for COVID-19, which is one of the clinical studies for Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV). With an existing clinical trial infrastructure and multiple support contracts to provide services related to clinical trials support, regulatory support and pharmacy support, NIAID serves as the sponsor for the COVID-19 clinical trial entitled "A5401: Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID)" also known as ACTIV-2. The objective of ACTIV-2 is to evaluate the safety and efficacy of multiple investigational agents aimed at modifying the host immune response to SARS-CoV-2 infection, or directly enhancing viral control in order to limit disease progression.

Key facts

Abstract