Return to homepagePandemic Pact

Covid-related changes in Taste Epithelium

  • Funded by National Institutes of Health (NIH)
  • Total publications:0 publications

Grant number: 3R01DC014728-05S1

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2020
    2021

  • Known Financial Commitments (USD)

    $191,384

  • Funder

    National Institutes of Health (NIH)

  • Principal Investigator

    PROFESSOR Thomas Finger

  • Research Location

    United States of America

  • Lead Research Institution

    UNIVERSITY OF COLORADO DENVER

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Disease pathogenesis

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

PROJECT SUMMARY Disruption of the sense of taste is a common feature of COVID-19. The proposed supplement will investigate potential histopathological changes in taste buds and the surrounding epithelium of the tongue in patients who have lost their sense of taste during COVID-19. Biopsies of fungiform papillae will be obtained from a taste center in Germany which shall conduct psychophysical testing prior to sampling 4 fungiform papillae from patients recovering from COVID-19 - either with or without taste loss. We will analyze these samples molecularly and histologically to test for presence of residual virus and for changes in taste bud number, morphology or cellular composition.