Better understanding the long term effects of SARS-COV-2 and its relationship with neuropsychological, mental disorders, and pain

Covid-19 has been associated with pain conditions, mental disorders, neurological problems, and alterations in cognition. The persistence of these problems in infected individuals has been demonstrated. In turn, cognition is involved in language and speech issues, which also persevere after someone has a long time of Covid-19. However, the relationship between Covid-19, cognition, and its relationship with mental disorders and its consequences on language remains unknown. Additionally, mental disorders have a role in pain perception. An increase in symptoms of anxiety and depression has been related to pain conditions. More research is needed to elucidate the etiologic pathways between the neurologic and psychiatric effects associated with Covid-19 infection and ultimately inform on possible interventions. Therefore, this study will aim to evaluate the relationships between Covid-19 infection, neuropsychological alterations, and pain conditions mediated by mental health. The current longitudinal study draws on data from over 2400 individuals participating in the "Biobanque Quebecoise de la Covid-19" with follow-up data for controls and individuals with Covid-19 infections recruited in outpatient and inpatient settings.