Validation of self-collected sample types for implementation at the point of need in First Nations communities in British Columbia

This proposal aims to address health service challenges in First Nations communities in British Columbia, focused on COVID-19, RSV, and Influenza A/B testing. Factors such as remote locations, constrained healthcare infrastructure, and racism and discrimination contribute to disparities, including in respiratory virus incidence. Building on prior RSV/Influenza testing research with the First Nations Health Authority (FNHA), there is interest for non-invasive self-collection methods to contribute to culturally safe care. The objective is to validate self-collected saline gargle (SG) and oral/nasal (ON) swabs against healthcare worker-collected nasopharyngeal (NP) swabs for implementation in the FNHA community-based testing program. Methods involve a prospective validation of sample types at BC Children's Hospital and knowledge translation with FNHA in the form of a policy brief and culturally appropriate instruction materials. This study employs an innovative combination of clinical validation and knowledge translation to enhance First Nations' equitable healthcare access. Feasibility is supported by hospital infrastructure, preexisting FNHA partnerships, and validation funding from the BC Ministry of Health Innovation Initiative. The goal is to minimize traumatic health encounters, preserve autonomy, and to address the unique needs of First Nations communities, ultimately improving healthcare participation and outcomes.