Enterics, Diagnostics, Genomics & Epidemiology

Key facts

Disease
Shigellosis
Start & end year
2020
2022
Known Financial Commitments (USD)
$2,753,024
Funder
Gates Foundation
Research Location
United States of America
Lead Research Institution
University of Washington Foundation
Research Priority Alignment
N/A

Research Category
Epidemiological studies
Research Subcategory
Disease surveillance & mapping
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable

Abstract

to support a multi-center Shigella surveillance study to support the clinical development of vaccines against shigellosis

5 Publications linked via Europe PMC

Last Updated:3 days ago

View all publications at Europe PMC

Robust performance of culture, real-time PCR, and genomic approaches for shigella serotyping in a pediatric surveillance cohort.

Fecal biomarkers to characterize intestinal inflammation among children with medically attended diarrhea across six low-resource settings: Findings from the Enterics for Global Health (EFGH) Shigella surveillance study.

Authors
Horne B, Otieno Onyando B, Badji H, Mujahid W, Bhuiyan TR, Bakali M, Iqbal J, Olortegui MP, Pavlinac P, Ceesay BE, Schultes O, Tennant SM, Ogwel B, Witte D, Atlas H, Ahmed N, Ochieng JB, Sears K, Islam S, Saidi Q, Jallow SJ, Hussain Z, Garcia Bardales P, Platts-Mills JA, Omore R, Khanam F, Mosharraf MP, Secka O, Munthali V, Kosek MN, Ndalama M, Cornick J, Yousafzai MT, Hossain MJ, Sonye C, Qadri F, Rogawski McQuade ET, Brennhofer SA.
Publish Year
2026
Journal
PLoS neglected tropical diseases
DOI
10.1371/journal.pntd.0014320

View at Europe PMC

Defining Severe Shigellosis in the Enterics for Global Health Study: A Comparison of Leading Diarrhea Severity Definitions Among Children With Shigella Diarrhea.

Authors
Schultes OL, Hotwani A, Pavlinac PB, Hossain MJ, Nasrin D, Omore R, Khanam F, Kawonga F, Garcia Bardales PF, Atlas HE, Awuor AO, Badji H, Conteh B, Cornick J, Feutz E, Galagan SR, Gitteh E, Houpt ER, Iqbal J, Islam S, Kabir F, Keita AM, Liu J, Mategula D, Mhango C, Mosharraf MP, Ogwel B, Okonji C, Onwuchekwa UU, Pinedo Vasquez T, Raz SMAA, Romaina-Cachique L, Schiaffino F, Tapia MD, Tennant SM, Yousafzai MT, Jere KC, Kosek MN, Sow SO, Platts-Mills JA, Qamar FN, Rogawski McQuade ET, Kotloff KL, Ochieng JB, Qadri F, EFGH Consortium .
Publish Year
2026
Journal
The Journal of infectious diseases
DOI
10.1093/infdis/jiaf630

View at Europe PMC

Optimizing Shigella isolation: a multi-site evaluation of laboratory culture methods for Shigella detection, speciation, and serotyping with different transport media and sample types in the Enterics for Global Health study.

Authors
Bhuiyan MTR, Liu J, Juma J, Horne B, Hotwani A, Badji H, Maiden VA, Ochieng JB, Romaina-Cachique LA, Aluoch LR, Ambila LA, Aziz F, Charles M, Feutz EL, Garcia Bardales PF, Hossain MJ, Iqbal J, Islam MT, Jabang A, Jarju S, Jere KC, Kabir F, Kawonga F, Keita AM, Khanam F, Manzanares Villanueva K, Mosharraf MP, Omore R, Paredes Olortegui M, Pavlinac PB, Platts-Mills JA, McQuade ETR, Saidi Q, Sears KT, Tapia MD, Traore A, Qadri F, Penataro Yori P, Qamar FN, Sow SO, Kotloff KL, Tennant SM, Houpt ER, Cornick J, Secka O, EFGH Consortium.
Publish Year
2026
Journal
Journal of clinical microbiology
DOI
10.1128/jcm.01279-25

View at Europe PMC

The incidence and antimicrobial resistance of Shigella-attributable diarrhoea in young children in low-income and middle-income countries from the multicountry Enterics for Global Health (EFGH) Shigella Surveillance Study: a prospective, facility-based hybrid surveillance study.

Authors
Yousafzai MT, Cornick J, Penataro Yori P, Hossain MJ, Keita AM, Atlas HE, Khanam F, Omore R, Galagan SR, Ahmed N, Ahmmed F, Awuor AO, Badji H, Conteh B, Garcia Quesada M, Garcia-Bardales PF, Horne B, Hotwani A, Houpt ER, Islam MT, Jere KC, Juma J, Liu J, Mategula D, Ogwel B, Okonji C, Onwuchekwa UU, Paredes Olortegui M, Platts-Mills JA, Qureshi S, Rajib MNH, Rogawski McQuade ET, Schiaffino F, Secka O, Sow SO, Witte D, Kotloff KL, Cunliffe NA, Clemens JD, Tennant SM, Qamar FN, Kosek MN, Pavlinac PB, Tapia MD, Ochieng JB, EFGH Consortium.
Publish Year
2026
Journal
The Lancet. Global health
DOI
10.1016/s2214-109x(25)00534-0

View at Europe PMC

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Enterics, Diagnostics, Genomics & Epidemiology

Key facts

Abstract

5 Publications linked via Europe PMC

Robust performance of culture, real-time PCR, and genomic approaches for shigella serotyping in a pediatric surveillance cohort.

Authors

Publish Year

Journal

DOI

Fecal biomarkers to characterize intestinal inflammation among children with medically attended diarrhea across six low-resource settings: Findings from the Enterics for Global Health (EFGH) Shigella surveillance study.

Authors

Publish Year

Journal

DOI

Defining Severe Shigellosis in the Enterics for Global Health Study: A Comparison of Leading Diarrhea Severity Definitions Among Children With Shigella Diarrhea.

Authors

Publish Year

Journal

DOI

Optimizing Shigella isolation: a multi-site evaluation of laboratory culture methods for Shigella detection, speciation, and serotyping with different transport media and sample types in the Enterics for Global Health study.

Authors

Publish Year

Journal

DOI

The incidence and antimicrobial resistance of Shigella-attributable diarrhoea in young children in low-income and middle-income countries from the multicountry Enterics for Global Health (EFGH) Shigella Surveillance Study: a prospective, facility-based hybrid surveillance study.

Authors

Publish Year

Journal

DOI